Maneesh Jain:

Hi, my name is Maneesh Jain. I'm a hematologist oncologist at the Washington, DC, VA Medical Center. I also have an associate professor title at George Washington University. I'm excited to give you guys an update on several veterans who are part of the CaRPET Trial. This is a trial that has started at the Washington, DC VA Medical Center, and we're very happy to give an update on the first patient who is Mr. Gary Wilson.

So Mr. Wilson is a 64-year-old veteran who started treatment with trastuzumab deruxtecan in August of 2024. As of February of 2026, he's been on therapy for a little bit more than six months.

Gary Wilson:

There's different kind of pains. I kept telling them that this pain I'm getting now is very deep. The cancer has spread from one lymph node to my cranial, to my clavicle, to my rib, to my spine, to my legs.

Maneesh Jain:

When he came and saw me, he had very aggressive prostate cancer that had failed several lines of treatment, and he was looking for another option to hopefully get him to feel better.

Gary Wilson:

To have a peace of mind by the progress of those drugs that they were giving me for my cancer. Like I said, I had a new aspect of life now. Dr. Jain, very good doctor and I explained to him there's nothing in the world right now I wouldn't try. I did not think I was going to survive this cancer. Just seeing like two or three years later, he called me and said that we're doing this study. I said, "Sign me up," even before he finished.

Maneesh Jain:

So we received scans two days ago, which is in February of 2026. The CT scans show no change in his disease, no evidence of progression. His PET bone scan that was done in February of 2026 compared to November showed that the disease was the same as it was then. Of note, the scans in November 2025 had showed a significant improvement in his disease compared to when he started on the trial.

Gary Wilson:

Now it is a totally different story. I can see my grandkids grow up. I can hug and talk to my family.

Maneesh Jain:

I'm excited to give an update on another veteran patient, Mr. Proctor. He's an 80-year-old veteran who has metastatic castrate-resistant prostate cancer. I've been following him for the last two to three years.

John Proctor:

When I came here for treatment, my PSA was pretty high. When I say pretty high, it was eight or nine-something. Since I've been receiving treatment here, my PSA has dropped down to 2, 2.0. The highest it's been is 3.8. But it's been pretty good.