Glossary of Terms

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Term Definition
CAR-T Therapy

A form of immunotherapy.


Block adrogen production at the site of the testitcles.

Castrate sensitive prostate cancer (CSPC) or Hormone sensitive prostate cancer (hSPC)

Prostate cancer that has never been treated with hormone therapy (ADT).

Castrate-resistant prostate cancer (CRPC)

Prostate cancer that is resistant to hormones via androgen depletion therapy (ADT).

Cell-cycle progression score

A genetic test that can determine how quickly prostate cancer is growing. The brand name is Prolaris.


A treatment that uses drugs to stop the growth of cancer cells, either by killing the cells or by stopping them from dividing. Chemotherapy may be given by mouth, injection, or infusion, or on the skin, depending on the type and stage of the cancer being treated. It may be given alone or with other treatments, such as surgery, radiation therapy, or biologic therapy.

Cognitive prostate biopsy

A biopsy procedure that uses both MRI scans and ultrasound images to guide the needle.

Computed tomography (CT) scan

A CT scan uses x-rays to make detailed, cross-sectional images of your body. This test isnÕt often needed for newly diagnosed prostate cancer if the cancer is likely to be confined to the prostate based on other findings (DRE result, PSA level, and Gleason score).


A class of steroids made in the body by the adrenal glands. They are also produced as a drug to help reduce inflammation in the body and support the immune system.

Cribriform tumor pattern

A pattern seen under the microscope in cancer cells that looks like small holes or open spaces.


A treatment that cools the prostate tumor to freeze and kill it.


An examination of the urethra and bladder that uses a small, thin tube with a light and camera that is inserted into the urethra. This allows the doctor to see inside and also take any samples needed.